Diphenhydramine hydrochloride, the active substance of Dermodrin, is an antihistamine and antiallergic agent, an anti-itching agent and relieves pain in allergies and skin conditions.
Dermodrin ointment, as an oil-in-water emulsion, has a cooling effect.
Dermodrin ointment is intended for external use only.
The creamy, white, totally non-irritant and odourless preparation can be easily rubbed in and spread over the skin.
The effect sets in shortly after applying the ointment and lasts for 2-6 hours.
Therapeutic indications:
Dermodrin ointment is used to treat itching, local pain and hypersensitivity reactions of the skin in cases of:
- allergies;
- insect stings;
- eczema, nettle rash, itchy wound edges and skin abrasions;
- minor burns, sunburn;
- itchy skin rash after sun exposure (sun allergy).
Do not use Dermodrin ointment- if you are allergic to diphenhydramine hydrochloride, other antihistamines, peanuts or soya or any of the other ingredients of this medicine;
- in newborn infants and children under 2 years of age;
- on open wounds or mucous membranes, extensive skin changes such as inflamed and injured skin, especially in patients suffering from chickenpox, shingles or measles or in cases of skin blistering.
Pregnancy and breast-feedingIf you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
Dermodrin ointment must not be used in the first 3 months of pregnancy.
During the remainder of the pregnancy, Dermodrin should be used only after careful benefit/risk assessment by the doctor and after the individual dose has been established.
Application over large areas must be avoided, especially on inflamed and injured skin.
The routine use of diphenhydramine in pregnancy is generally not recommended due to the lack of controlled clinical studies [this applies particularly to the last 2 weeks of pregnancy].
Dermodrin ointment must not be used during breast-feeding, as the active substance (diphenhydramine) passes into breast milk.
This is an OTC drug, so it can be taken without a doctor's recommendation.
Before using this medicine read carefully the package leaflet as it contains more detailed information.
For any uncertainty consult your doctor or pharmacist.

Adults and adolescents aged 12-18 years apply a ribbon of ointment 5-15 cm long (equivalent to 18-54 mg diphenhydramine) to the affected skin area 3 – 4 times daily, depending on the size of the site to be treated.
The daily dose of 300 mg diphenhydramine hydrochloride, equivalent to 15 g Dermodrin ointment, must not be exceeded.
300 mg is equivalent to 3/4 of a 20 g tube, 1/3 of a 50 g tube and 1/6 of a 100 g tube.
For children aged 6 – 11 years, a ribbon of ointment about 8-10 cm long is applied 3 – 4 times daily.
The maximum daily dose of 150 mg diphenhydramine (equivalent to a 41 cm ribbon of ointment/day) must not be exceeded.
For children aged 2 – 5 years, a ribbon of ointment about 3 cm long is applied 2 – 3 times daily;
the maximum daily dose of 37 mg diphenhydramine (equivalent to a 10 cm ribbon of ointment/day) must not be exceeded.
The duration of treatment should be as short as possible.

diphenhydramine hydrochloride, methylhydroxybenzoate (0.
15% g/g), peanut oil, bleached wax, cetylalcohol, hard paraffin, white Vaseline, glycerol, Hostacerin T-3, polysorbate 80, isobornyl acetate, sodium hydroxide for pH adjustment, purified water.