Clotri-Denk 1% cream is a pharmaceutical agent for the treatment of fungal disease of the skin and mucous membrane, caused by dermatophytes, yeasts, moulds and other fungi such as Malassezia furfur and skin infections caused by Corynebacterium minutissimum.
These may occur, for examle, in the form of:
-foot mycoses (athele's foot), between the toes and fingers, at the base of the nail, also in combination with nail mycoses;
-skin diseases which are superinfected with clotrimazole-sensitive pathogens;
-mycoses of the skin and skin folds;
-superficial candidiasis;
-pityriasis versicolor;
-infections with Corynebacterium minutissimum;
-seborrheic dermatitis only with microbial involvement or other pathogens;
-infections of the labia and adjoining areas caused by yeasts;
-inflammations of the male glands and foreskin by yeast-type fungi.
Clotrimazole, the active ingredient in Clotri-Denk 1% Cream, penetrates the affected skin and attacks the fungus.
This results in fungal death or growth inhibition.
Do not use Clotri-Denk 1% Cream if you are allergic to clotrimazole, cetylstearyl alcohol or any of the other ingredients of Clotri-Denk 1% Cream.
No interections with other medicines have been reported so far.
Pregnancy and breastfeeding - Ask your doctor or pharmacist for advice before taking any medicine.
Pregnancy - if you use this cream as prescribed in the dosage instructions or as recommended by your doctor of pharmacist, the active ingredient clotrimazole is only absorbed by the body in very small quantities.
A systemic effect can therefore be excluded.
As a precaution clotrimazole may be used during pregnancy, if applied to the vagina, after appropriate consideration of the benefits and risks by the doctor in attendance.
Breastfeeding - Because of the low level of absorption if used on the skin or mucous membranes, breast-feeding probably involves no risk to the infant.
During lactation, Clotri-Denk 1% Cream should not be applied directly to the breast producing milk.
Driving and using machines - No particular precautionary measures are necessary.
Important information about some of the ingredients of Clotri-Denk 1% Cream:
-cetylstearyl alcohol can cause local skin irritation (e.
g contact dermatitis).
Note - if Clotri-Denk 1% Cream is used at the same time as latex products (e.
g condoms, diaphragms), it may cause a decrease in function because of the excipients contained (especially stearates) and thus have an adverse effect on the reliability of these products.
If you use more Clotri-Denk 1% Cream than you should - the consequences are unknown.
No reports of overdose have been received.
If you forget to use Clotri-Denk 1% Cream:
Do not use more Clotri-Denk 1% Cream the next time;
simply continue the treatment as recommended.
If you stop using Clotri-Denk 1% Cream:
To make sure that the fungal infection has completely cleared up and to prevent any recurrence, you should stop the treatment too early or interrupt it without consulting your doctor.
Otherwise, there is a risk that the symptoms may reapear, since your fungal disease will probably not have been completely healed.
You should also systematically continue with the treatment even after the symptoms have disappeared.
If you have any other furthet question on the use of this product, ask your doctor or pharmacist.
What else can you do?Change any towels, underwear and socks or stockings that come into contact with the affected skin area each day.
Even this simple measure supports healing and stops any transmission to other parts of the body and other people.
Possible side effects:
Like all medications, Clotri-Denk 1% Cream can cause side effects, although nor everybody gets them.
The frequency of adverse drug reactions is classified as follows:
-very common (more than 1 out of 10 patients treated);
-common (1 to 10 out of 100 patients treated);
-uncommon (1 to 10 out of 1000 patients treated);
-rare (1 to 10 out of 10000 patients treated);
-very rare (fewer than 1 out of 10000 patients treated);
-not known (the frequency cannot be assessed on the basis of the available data).
Possible side effects:
-skin and subcutaneous tissue disorders (uncommon:
temporary irritant skin reactions, such as burning, stinging, redening);
-hypersensitivity reactions (in the event of hypersensitivity to cetylstearyl alcohol, allergic reactions of the skin/mucous membrane may occour.
If any of the side effects becomes serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
How to store Clotri-Denk 1% Cream?Store at a temperature between 2-30˚C.
Keep the tube tightly closed.
Discard 1 year after opening.
Do not use after the expiry date.
Keep out the reach and sight of children.
For further information on pharmacological and pharmacokinetic properties read the leaflet.
For external use only.